Commercial-scale Bio-Pro FPLC systems with quaternary diaphragm pumps, mass-flow metering, and process-ready UV/pH/conductivity options for protein and peptide purification.
Applications, Features & Benefits
- Biologics manufacturing
- Commercial protein purification
- Process chromatography
- Quaternary diaphragm pump — isocratic (S) single / gradient (G) dual
- E+H mass flow metering
- OPTEK or ECOM UV options
- HAMILTON pH and conductivity
DSP can recommend a configuration for your workflow.
Technical parameters
Showing 18 rows
| Bio-Pro30 | Bio-Pro100 | Bio-Pro150 | Bio-Pro600 | Bio-Pro1200 | Bio-Pro2500 | Bio-Pro4400 | |
|---|---|---|---|---|---|---|---|
| Pump | Quaternary diaphragm pump — isocratic (S) single pump; gradient (G) dual pump | Quaternary diaphragm pump — isocratic (S) single pump; gradient (G) dual pump | Quaternary diaphragm pump — isocratic (S) single pump; gradient (G) dual pump | Quaternary diaphragm pump — isocratic (S) single pump; gradient (G) dual pump | Quaternary diaphragm pump — isocratic (S) single pump; gradient (G) dual pump | Quaternary diaphragm pump — isocratic (S) single pump; gradient (G) dual pump | Quaternary diaphragm pump — isocratic (S) single pump; gradient (G) dual pump |
| Flow range | 0.5–48 L/h | 3–100 L/h | 6–180 L/h | 10–600 L/h | 20–1200 L/h | 100–2500 L/h | 300–4000 L/h |
| Flow accuracy | Single pump: 1× E+H mass flow meter; dual pump: 2× E+H. Detection ±0.5%, system flow ±2% | Single pump: 1× E+H mass flow meter; dual pump: 2× E+H. Detection ±0.5%, system flow ±2% | Single pump: 1× E+H mass flow meter; dual pump: 2× E+H. Detection ±0.5%, system flow ±2% | Single pump: 1× E+H mass flow meter; dual pump: 2× E+H. Detection ±0.5%, system flow ±2% | Single pump: 1× E+H mass flow meter; dual pump: 2× E+H. Detection ±0.5%, system flow ±2% | Single pump: 1× E+H mass flow meter; dual pump: 2× E+H. Detection ±0.5%, system flow ±2% | Single pump: 1× E+H mass flow meter; dual pump: 2× E+H. Detection ±0.5%, system flow ±2% |
| Inlet / outlet valves | Inlet: 2–8 (single) / 4–16 (dual); Outlet: 2–8 | Inlet: 2–8 (single) / 4–16 (dual); Outlet: 2–8 | Inlet: 2–8 (single) / 4–16 (dual); Outlet: 2–8 | Inlet: 2–8 (single) / 4–16 (dual); Outlet: 2–8 | Inlet: 2–8 (single) / 4–16 (dual); Outlet: 2–8 | Inlet: 2–8 (single) / 4–16 (dual); Outlet: 2–8 | Inlet: 2–8 (single) / 4–16 (dual); Outlet: 2–8 |
| Pressure sensor | 2× LABOM, 0–10 bar, ± ±0.1 bar | 2× LABOM, 0–10 bar, accuracy ±0.1 bar | 2× LABOM, 0–10 bar, accuracy ±0.1 bar | 2× LABOM, 0–10 bar, accuracy ±0.1 bar | 2× LABOM, 0–10 bar, accuracy ±0.1 bar | 2× LABOM, 0–10 bar, accuracy ±0.1 bar | 2× LABOM, 0–10 bar, accuracy ±0.1 bar |
| Bubble detector | SONOTEC at inlet & precolumn, or AQ bubble sensor (adjustable) | SONOTEC at inlet & precolumn, or AQ bubble sensor (adjustable) | SONOTEC at inlet & precolumn, or AQ bubble sensor (adjustable) | SONOTEC at inlet & precolumn, or AQ bubble sensor (adjustable) | SONOTEC at inlet & precolumn, or AQ bubble sensor (adjustable) | SONOTEC at inlet & precolumn, or AQ bubble sensor (adjustable) | SONOTEC at inlet & precolumn, or AQ bubble sensor (adjustable) |
| UV | OPTEK fixed (280/254 nm), 0–3 AU; or ECOM variable 4-λ (200–400 nm), 0–5 AU | OPTEK fixed (280/254 nm), 0–3 AU; or ECOM variable 4-λ (200–400 nm), 0–5 AU | OPTEK fixed (280/254 nm), 0–3 AU; or ECOM variable 4-λ (200–400 nm), 0–5 AU | OPTEK fixed (280/254 nm), 0–3 AU; or ECOM variable 4-λ (200–400 nm), 0–5 AU | OPTEK fixed (280/254 nm), 0–3 AU; or ECOM variable 4-λ (200–400 nm), 0–5 AU | OPTEK fixed (280/254 nm), 0–3 AU; or ECOM variable 4-λ (200–400 nm), 0–5 AU | OPTEK fixed (280/254 nm), 0–3 AU; or ECOM variable 4-λ (200–400 nm), 0–5 AU |
| pH | HAMILTON, 0–14, ± ±0.1; online calibration with report | HAMILTON, 0–14, accuracy ±0.1; online calibration with report | HAMILTON, 0–14, accuracy ±0.1; online calibration with report | HAMILTON, 0–14, accuracy ±0.1; online calibration with report | HAMILTON, 0–14, accuracy ±0.1; online calibration with report | HAMILTON, 0–14, accuracy ±0.1; online calibration with report | HAMILTON, 0–14, accuracy ±0.1; online calibration with report |
| Conductivity | HAMILTON 1 µS–300 mS/cm or OPTEK 1 µS–850 mS/cm | HAMILTON 1 µS–300 mS/cm or OPTEK 1 µS–850 mS/cm | HAMILTON 1 µS–300 mS/cm or OPTEK 1 µS–850 mS/cm | HAMILTON 1 µS–300 mS/cm or OPTEK 1 µS–850 mS/cm | HAMILTON 1 µS–300 mS/cm or OPTEK 1 µS–850 mS/cm | HAMILTON 1 µS–300 mS/cm or OPTEK 1 µS–850 mS/cm | HAMILTON 1 µS–300 mS/cm or OPTEK 1 µS–850 mS/cm |
| Tubing material | ASME BPE (316L SS), Ra ≤ 0.4 µm | ASME BPE (316L SS), Ra ≤ 0.4 µm | ASME BPE (316L SS), Ra ≤ 0.4 µm | ASME BPE (316L SS), Ra ≤ 0.4 µm | ASME BPE (316L SS), Ra ≤ 0.4 µm | ASME BPE (316L SS), Ra ≤ 0.4 µm | ASME BPE (316L SS), Ra ≤ 0.4 µm |
| System pressure | 6 bar | 6 bar | 6 bar | 6 bar | 6 bar | 6 bar | 6 bar |
| Bubble trap volume | 50 ml | 100 ml | 500 ml | 1000 ml | 2500 ml | 5000 ml | 5000 ml |
| Tubing size | 1/8" | 1/4" | 3/8" | 1/2" | 3/4" | 1" | 1.5" |
| Power supply | 220 VAC 50 Hz | 220 VAC 50 Hz | 220 VAC 50 Hz | 220 VAC 50 Hz | 220 VAC 50 Hz | 380 VAC 50 Hz | 380 VAC 50 Hz |
| Power | 1 kW | 1 kW | 1 kW | 1 kW | 1.5 kW | 3 kW | 5 kW |
| Dimensions (cm)① | 103 H × 63 W × 98 D | 118 H × 70 W × 105 D | 118 H × 70 W × 105 D | 123 H × 70 W × 113 D | 123 H × 80 W × 120 D | 180 H × 150 W × 180 D | 180 H × 150 W × 180 D |
| Weight② | 140 kg | 150 kg | 180 kg | 200 kg | 280 kg | 580 kg | 780 kg |
| Utilities | Compressed air 5–7 bar, OD 10 mm air hose | Compressed air 5–7 bar, OD 10 mm air hose | Compressed air 5–7 bar, OD 10 mm air hose | Compressed air 5–7 bar, OD 10 mm air hose | Compressed air 5–7 bar, OD 10 mm air hose | Compressed air 5–7 bar, OD 10 mm air hose | Compressed air 5–7 bar, OD 10 mm air hose |
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